目的研究经直肠超声弹性成像前列腺穿刺活检在提高前列腺癌检出率中的作用和临床意义。方法对95例血清PSA异常或直肠指诊异常患者行直肠超声弹性成像前列腺穿刺活检,穿刺方案为10点系统穿刺加经直肠超声弹性成像异常处穿刺,对比穿刺结果,研究经直肠超声弹性成像异常部位的穿刺在提高前列腺癌检出率中的作用。结果95例疑似前列腺癌患者均顺利完成穿刺,成功率为100%,其中病理证实为前列腺癌44例,占46.31%(44/95),采用10点系统穿刺法阳性率为31例,占32.63%(31/95),经直肠超声弹性成像异常处穿刺阳性为37例,占38.95%(37/95),通过对经直肠超声弹性成像异常处穿刺能提高穿刺阳性率14.75%(14/95)(P<0.05)。10点系统穿刺数目为950针,阳性针数目为135针,阳性率为14.21%,经直肠超声弹性成像异常处穿刺数目为197针,阳性针数目为103针,阳性率为52.28%,明显高于10点系统穿法(P<0.001)。TRE诊断前列腺癌具有明显的特异性88.24%(45/51),与DRE及TURS的特异性比较,差异具有统计学意义(P<0.05)。结论经直肠超声弹性成像技术能提高前列腺癌的检出率。 Objective To study the role and clinical significance of transrectal ultrasound elastography in prostate biopsy in detecting prostate cancer. Methods Ninety-five patients with abnormal PSA or abnormality of digital rectal examination underwent transrectal ultrasound guided prostate biopsy. The puncture protocol was punctured by 10-point system puncture and transrectal ultrasound elastography. The results of transrectal ultrasound elastography were compared Site puncture in improving the detection rate of prostate cancer role. Results 95 cases of suspected prostate cancer patients successfully puncture, the success rate was 100%, of which pathologically confirmed 44 cases of prostate cancer, accounting for 46.31% (44/95), the use of 10-point system biopsy positive rate was 31 cases, accounting for 32.63 % (31/95). Thirty-seven cases (38.95%) were diagnosed by transrectal ultrasound elastography. The positive rate of transabdominal puncture was 14.75% (14/95 ) (P <0.05). The number of 10-point system puncture was 950, the positive number of needle was 135 and the positive rate was 14.21%. The number of puncture was 197 and the number of positive needle was 103, the positive rate was 52.28% Systemic wears at 10:00 (P <0.001). The specificity of TRE for the diagnosis of prostate cancer was 88.24% (45/51), which was significantly different from the specificity of DRE and TURS (P <0.05). Conclusion Transrectal ultrasound elastography can improve the detection rate of prostate cancer.