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本实验用日本大耳白兔复制输精管结扎的长期动物模型，分为结扎２５月组（ＶＧ２５），同龄假手术２５月组（ＳＯＧ２５）；结扎６月组（ＶＧ６），同龄假手术６月组（ＳＯＧ６）。记录各组家兔心功能，检测心肌及血清ＮＥ含量，称取心重（ＷＨ）。结果表明，左心室收缩期末压（ＬＶＳＰ），ＶＧ略高于ＳＯＧ；左心室舒张末压（ＬＶＥＤＰ），Ｖ６２５显著的低于ＳＯＧ２５Ｐ＜０．０５），ＶＧ６与５ＯＧ６比较虽无显著差异，也呈低值；±ｄｐ／ｄｔｍａｘ，ＶＧ均明显高于ＳＯＧ（Ｐ＜０．０１）。相关检验表明，＋ｄｐ／ｄｔｍａｘ与血清及心肌ＮＥ含量无相关性；心重与＋ｄｐ／ｄｔｍａｘ呈明显正相关，Ｐ＜０．０５；在２５月组，ＬＶＳＰ与＋ｄｐ／ｄｔｍａｘ呈正相关，Ｐ＜０．０５。提示输精管结扎可提高心肌收缩功能。
In this study, long-term animal models of vas deferens ligation were performed in Japanese white rabbits. They were divided into VG25 group (25 months), SOG25 group (SOG25 group), VG6 group (SOG6). The heart function of rabbits in each group was recorded, the content of NE in myocardium and serum was measured, and the heart weight (WH) was weighed. The results showed that left ventricular end-systolic pressure (LVSP), VG slightly higher than SOG; left ventricular end-diastolic pressure (LVEDP), V625 was significantly lower than SOG25P <0.05), VG6 and 5OG6 no significant difference Low values; ± dp / dtmax, VG were significantly higher than SOG (P <0.01). The correlation test showed that there was no correlation between + dp / dtmax and serum and myocardial NE content. The cardiac weight was positively correlated with + dp / dtmax, P <0.05. In 25 months, LVSP was positively correlated with + dp / dtmax, P < 0.05. Tip vasectomy can improve myocardial systolic function.