已有人报道,在小鼠骨髓液体培养基中,有一种淋巴因子能刺激嗜曙红细胞(eosinophils)分化。这一因子相当于一种集落刺激因子(CSF)。在本文中,作者报道这种因了有B细胞生长因子Ⅱ(BCGFⅡ)的活性。已知T细胞杂交瘤NIMP-TH1能分泌嗜曙红细胞分化因子(EDF)而不分泌任何其它淋巴因子。一系列试验表明EDF与IL-2,rIFN、IL-3、以及 It has been reported that a lymphokine stimulates the differentiation of eosinophils in mouse bone marrow fluid media. This factor is equivalent to a colony stimulating factor (CSF). In this article, the authors report that this is due to the activity of B-cell growth factor II (BCGFII). The T cell hybridoma NIMP-TH1 is known to secrete eosinophil differentiation factor (EDF) without secreting any other lymphokines. A series of tests showed that EDF and IL-2, rIFN, IL-3, and