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目的探讨超声与CT引导下射频消融联合靶向治疗肺癌的临床疗效。方法 90例肺癌患者,随机分为对照组和实验组,各45例。对照组患者应用吉非替尼、顺铂联合紫杉醇靶向治疗,实验组患者在对照组治疗基础上加用超声与CT引导下射频消融治疗,观察比较两组患者近期治疗效果、整体功能评分差异。结果实验组患者客观有效率为66.67%,高于对照组的51.11%(P<0.05);实验组患者情绪、躯体、认知、角色和社会功能整体功能评分均明显高于对照组(P<0.05)。结论针对肺癌患者采用超声与CT引导下射频消融术和靶向治疗明显提高治疗效果,改善患者生活质量,其为安全性高、创伤小的治疗方案,临床值得推广应用。
Objective To investigate the clinical efficacy of ultrasound and CT-guided radiofrequency ablation combined with targeted therapy in the treatment of lung cancer. Methods Ninety patients with lung cancer were randomly divided into control group and experimental group, each with 45 cases. Patients in the control group were treated with gefitinib and cisplatin combined with paclitaxel. The patients in the experimental group were treated with radiofrequency ablation by ultrasound and CT under the control group. The short-term therapeutic effect and overall functional score were compared between the two groups . Results The objective effective rate in the experimental group was 66.67%, which was higher than that in the control group (51.11%, P <0.05). The overall functional scores of emotion, body, cognition, role and social function in the experimental group were significantly higher than those in the control group (P < 0.05). Conclusion For patients with lung cancer, radiofrequency ablation and targeted radiofrequency ablation guided by CT and CT can obviously improve the therapeutic effect and improve the quality of life of patients. It is a safe and traumatic treatment plan, which is worthy of clinical application.