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目的:探讨穴位封闭配合口服升白细胞(升白)药治疗抗甲状腺药物所致白细胞减少症的临床疗效。方法:将确诊的210例患者随机分为A、B、C3 组(各70 例)。A组口服维生素B4、利血生和碳酸锂;B组在A 组治疗基础上联合应用足三里穴、膈俞穴注射地塞米松及肌苷;C组应用粒细胞集落刺激因子(G CSF)皮下注射,3 组均在治疗后第3、5、10日各查血象1次,进行疗效评定。结果:3 组患者总有效率分别为35.7% 、90.0%和100.0% 。B组总有效率显著优于A组(P< 0.01),B、C2 组疗效相近(P> 0.05)。结论:穴位封闭配合口服升白药治疗抗甲状腺药所致白细胞减少症,疗效明显高于单纯口服升白药者,与应用G CSF疗效相近。
Objective: To investigate the clinical efficacy of anti-thyroid drug-induced leukopenia treated by acupuncture combined with oral leukocyte (lightening) agents. Methods: 210 patients were randomly divided into A, B, C3 group (70 cases each). Group A was given vitamin B4, reserpine and lithium carbonate; group B was treated with Zusanli (ST 36) and Geshu (group) injection of dexamethasone and inosine on the basis of group A; Group C was given granulocyte colony stimulating factor Subcutaneous injection, the three groups were on the 3rd, the 5th and 10th after each check blood test 1, the curative effect was evaluated. Results: The total effective rates of the three groups were 35.7%, 90.0% and 100.0% respectively. The total effective rate in group B was significantly better than that in group A (P <0.01). The efficacy in group B and C2 was similar (P> 0.05). Conclusion: Acupoint combined with oral Baiyao drug treatment of anti-thyroid drug-induced leukopenia, the effect was significantly higher than pure oral whitening agents, and the application of G CSF is similar.