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目的:探讨儿童重症社区获得性肺炎患儿血清平均血小板体积(mean platelet volume,MPV)水平及其临床意义,为儿童SCAP的严重程度判断提供更多临床的依据。方法:646例社区获得性肺炎患儿根据肺炎病情的轻重分为SCAP组56例和非SCAP组590例,对照组为100例正常体检患儿,收集其临床资料及实验室指标进行分析。结果:儿童CAP组PCT、MVP水平明显高于正常对照组(P<0.01),两组血WBC、CRP水平差异无统计学意义(P>0.05)。儿童SCAP组MVP水平明显高于非SCAP组(P<0.01),两组血WBC、CRP、PCT水平差异无统计学意义(P>0.05)。结论:MPV一定程度反映了儿童重症社区获得性肺炎的严重程度和炎症的程度。
Objective: To investigate the serum mean platelet volume (MPV) level and its clinical significance in children with severe community-acquired pneumonia and to provide more clinical evidence for judging the severity of SCAP in children. Methods: According to the severity of pneumonia, 646 children with community-acquired pneumonia were divided into 56 cases of SCAP group and 590 cases of non-SCAP group according to the severity of pneumonia. The control group was 100 cases of normal physical examination, and the clinical data and laboratory indexes were collected for analysis. Results: The levels of PCT and MVP in CAP group were significantly higher than those in normal control group (P <0.01). There was no significant difference in WBC and CRP levels between the two groups (P> 0.05). The level of MVP in children with SCAP was significantly higher than that in non-SCAP (P <0.01). There was no significant difference in WBC, CRP and PCT between the two groups (P> 0.05). CONCLUSIONS: MPV to some extent reflects the severity and severity of severe community-acquired pneumonia in children.