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目的对19例同种异体肾移植,1例胰肾联合移植资料进行分析、总结。方法统计肾移植术后1年人、肾存活率,人类组织相容性抗原(HLA)供受者之间配型以及群体反应抗体(PRA)检测情况。结果人肾存活率95%/95%,19例恢复工作,1例死亡,未出现外科并发症,术后4例出现加速排斥反应,2例出现急性排斥反应。结论充分的术前准备和高质量的供肾是提高手术成功率的保证;严格的HLA配型和术后合理用药是提高长期存活的关键;免疫抑制剂合理使用可降低感染的发生率。
Objective To analyze and summarize the data of 19 cases of allogeneic kidney transplantation and 1 case of pancreas-kidney transplantation. Methods The renal allo-renal survival rate, the distribution of human histocompatibility antigen (HLA) donor and the detection of population reaction antibody (PRA) were calculated after 1 year of renal transplantation. Results The survival rate of human kidney was 95% / 95%. Nineteen patients recovered, one died and no surgical complications occurred. Four patients had accelerated rejection after operation and two patients had acute rejection. Conclusion Sufficient preoperative preparation and high quality donor kidney are the guarantee to improve the success rate of operation. Strict HLA matching and postoperative rational use of drugs are the keys to improve long-term survival. The rational use of immunosuppressive agents can reduce the incidence of infection.