目的:探究宽心合剂对颈动脉狭窄支架植入术后脑卒中影响研究。方法:108例颈动脉狭窄患者,根据患者的意愿,分成试验组和对照组,每组54例。对照组按CAS术后常规氯吡格雷与阿司匹林联用抗血小板方案,实验组在对照组的基础上联合使用宽心合剂进行治疗。于治疗后的1、3、6、12月,对两组患者的NIHSS评分、颈动脉TIA和新发脑梗死的发生率进行统计和比较;治疗后的6月和12月,对两组患者的血浆同型半胱氨酸水平(Plasma homocysteine levels,Hcy)进行对照比较;于治疗后的12月,对照比较两组患者的颈动脉狭窄处颈动脉彩超各参数的变化。结果:实验组患者在治疗后的1、3、6、12月NIHSS评分显著的低于对照组的患者(P<0.05);实验组患者在治疗后发生缺血性脑卒中、颈动脉TIA和新发脑梗死的发生率明显低于对照组患者(P<0.05);两组患者在治疗后的6月和12月Hcy均无明显差异(P>0.05);两组患者在治疗后的12月颈动脉狭窄处多普勒相关参数均无明显差异(P>0.05);实验组患者术后的不良反应发生率显著低于对照组(P<0.05)。结论:宽心合剂对颈动脉狭窄支架植入术,具有安全可靠的临床治疗效果,同时还可预防患者脑卒中的发生。 Objective: To investigate the effect of wide heart mixture on carotid artery stenosis after stent implantation stroke. Methods: 108 patients with carotid artery stenosis were divided into experimental group and control group according to the patients’ wishes, each group had 54 cases. In the control group, conventional anti-platelet combination of clopidogrel and aspirin was given after the CAS. The experimental group was treated with the combination of Kuanxin Mixture on the basis of the control group. At 1, 3, 6 and 12 months after treatment, the NIHSS score, carotid artery TIA and the incidence of new-onset cerebral infarction in both groups were statistically compared and compared; in June and December after treatment, Plasma homocysteine ​​levels (Hcy) were compared between the two groups. After 12 months of treatment, the changes of carotid ultrasonography parameters in two groups were compared. Results: The NIHSS scores of the experimental group were significantly lower than those of the control group at 1, 3, 6 and 12 months after treatment (P <0.05). The experimental group had ischemic stroke, carotid TIA and The incidence of new-onset cerebral infarction was significantly lower than that of the control group (P <0.05). There was no significant difference in Hcy between June and December after treatment in both groups (P> 0.05) There was no significant difference in the Doppler parameters of carotid artery stenosis (P> 0.05). The incidence of postoperative adverse reactions in the experimental group was significantly lower than that in the control group (P <0.05). Conclusions: Kuanxin Mixture has the safe and reliable clinical treatment effect for carotid stenosis stenting, and can prevent the occurrence of stroke in patients.