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AIM:To investigate the special Fourier transform infraredspectroscopy(FT-IR)spectra in normal and cancerous tissuesof esophagus.METHODS:Twenty-seven pairs of normal and canceroustissues of esophagus were studied by using FT-IR and thespecial spectra characteristics were analyzed in differenttissues.RESULTS:Different spectra were found in normal andcancerous tissues.The peak at 1 550/cm was weak andwide in cancerous tissues but strong and high in normaltissues.The ratio of I1 647/I1 550 was 2.0 in normal tissuesand 2.36 in cancerous tissues(P<0.05).The ratio of I1 550/1 1 080 was 4.5 in normal tissues and 3.4 in canceroustissues(P<0.01).The peak at 1453/cm was higher than at1 402/cm in normal tissue and lower than at 1 402/cm incancerous tissues.CONCLUSION:The results indicate that FTIR may be usedin clinical diagnosis.
A investigations into the special Fourier transform infrared spectroscopy (FT-IR) spectra in normal and cancerous tissues of esophagus. METHODS: Twenty-seven pairs of normal and cancerous lesions of esophagus were studied by using FT-IR and the spectroscopic spectra characteristics were analyzed in different tissues. RESULTS: Different spectra were found in normal and cancerous tissues. Peak at 1 550 / cm was weak andwide in cancerous tissues but strong and high in normal tissue. The ratio of I1 647 / I1 550 was 2.0 in normal tissues and 2.36 in cancerous tissues (P <0.05) .The ratio of I1 550/1 1 080 was 4.5 in normal tissues and 3.4 in canceroustissues (P <0.01). The peak at 1453 / cm was higher than at1 402 / cm in normal tissue and lower than at 1 402 / cm incancerous tissues. CONCLUSION: The results indicate that FTIR may be used in clinical diagnosis.