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目的探讨平阳霉素联合普萘洛尔治疗婴幼儿头面部血管瘤的临床疗效。方法 70例头面部血管瘤婴幼儿,随机分为观察组和对照组,各35例。对照组采用平阳霉素注射治疗,观察组给予平阳霉素注射治疗,同时给予普萘洛尔口服治疗。观察两组疗效。结果观察组不良反应发生率和对照组比较,差异无统计学意义(P>0.05)。观察组治疗后Ⅱ级和Ⅳ级患儿所占比例为68.6%,对照组治疗后Ⅱ级和Ⅳ级患儿所占比例为40.0%,前者高于后者,差异有统计学意义(P<0.05)。结论平阳霉素联合普萘洛尔治疗婴幼儿头面部血管瘤临床效果显著,值得借鉴。
Objective To investigate the clinical efficacy of bleomycin combined with propranolol in the treatment of infantile head and facial hemangiomas. Methods 70 cases of facial hemangiomas infants and young children were randomly divided into observation group and control group, 35 cases each. The control group was treated with pingyangmycin injection, the observation group was treated with pingyangmycin injection, while oral administration of propranolol. The two groups were observed. Results The incidence of adverse reactions in the observation group compared with the control group, the difference was not statistically significant (P> 0.05). The proportion of grade Ⅱ and grade Ⅳ children in the observation group was 68.6% after treatment, while the percentage of grade Ⅱ and Ⅳ grade children in the control group was 40.0%, the former was higher than the latter, the difference was statistically significant (P < 0.05). Conclusion Pingyangmycin combined with propranolol in the treatment of infantile head and facial hemangioma clinical results are significant, it is worth learning.