目前对仅以颈部淋巴结转移为主要症状,鼻咽部检查正常的早期隐性鼻咽癌的诊断,还比较困难。据统计,鼻咽癌大多数属于鳞癌,主要是浸润粘膜下层。早期鼻咽部粘膜表面可能无异常改变。鼻咽部随机取样活检,如果钳夹的组织深度不够,病理学报告也可能是正常。这种病人多以颈部出现不明肿物就诊。本文作者通过对2例仅在颈部发现不明原因的肿物,其它无任何症状,头颈部检查包括鼻咽部活检均为阴性患者的病理学研究,提出使用原位杂交法,在颈部淋巴结切片中,检测EB病毒,可以帮助 At present, it is difficult to diagnose early latent nasopharyngeal carcinoma with cervical lymph node metastasis as the main symptom and normal nasopharynx examination. According to statistics, most of the nasopharyngeal cancers are squamous cell carcinomas, mainly infiltrating the submucosa. There may be no abnormal changes in the mucosal surface of the early nasopharynx. A random sampling biopsy of the nasopharynx may also be normal if the tissue depth of the clamp is not sufficient. This type of patient often presents with an unknown mass on the neck. The authors of this study identified 2 patients with unexplained tumors on the neck only. Others had no symptoms. Head and neck examinations included pathological studies in patients with negative nasopharynx biopsy and proposed using in situ hybridization in the neck. Detection of EB virus in lymph node sections can help