骨质疏松症是最常见的代谢性骨病,其特征是低骨量及骨组织微结构改变,骨脆性增加并易患骨折的疾病。骨质疏松症是多因素的疾病,与遗传、生活方式等因素有关,但年龄的增加和绝经是导致骨质疏松的两个重要因素。随着年龄的增长,所有的人都会发生骨丢失,尤其是妇女卵巢功能衰竭后,雌激素不足使骨丢失明显加快。据流行病学调查约三分之一绝经后妇女患骨质疏松症,而50％绝经后妇女的骨折与骨质疏松有关。因此,应对绝经 Osteoporosis is the most common metabolic bone disease characterized by low bone mass and changes in the microstructure of bone tissue, increased bone fragility and susceptible to fractures. Osteoporosis is a multifactorial disease, and genetic and lifestyle factors, but age and menopause are two important factors leading to osteoporosis. With age, all people will have bone loss, especially in women after ovarian failure, estrogen deficiency significantly accelerated bone loss. About a third of postmenopausal women have osteoporosis, according to epidemiological investigations, while 50% of postmenopausal women have osteoporosis. Therefore, the response to menopause