磷酸奥司他韦治疗儿童甲型、乙型流行性感冒临床疗效及对炎性因子水平的影响

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目的:探究磷酸奥司他韦治疗儿童甲型、乙型流行性感冒临床疗效及对炎性因子水平的影响.方法:选取2019年11月~2020年01月本院收治甲型、乙型流行性感冒患儿100例,根据咽拭子胶体金法检测结果可分为甲型流感组74例,乙型流感组26例.比较甲型、乙型流行性感冒患儿经磷酸奥司他韦治疗后临床疗效以及炎性因子水平变化.结果:甲型流感组的治疗有效率显著高于乙型流感组,差异具有统计学意义(P<0.05).治疗后,两组的TNF-α、IL-6、CRP水平显著低于治疗前的水平(P<0.05),甲型流感组的TNF-α、IL-6、CRP降低水平显著高于乙型流感组的水平(P<0.05).结论:磷酸奥司他韦治疗甲型流行性感冒患儿的临床疗效优于乙型流行性感冒患儿,可能与炎性因子水平有关.
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