目的:对31例肝炎综合征并颅内出血患儿进行临床分析,探讨婴儿肝炎综合征与颅内出血的关系。方法:回顾云南省大理州妇幼保健院1997-01/2007-10收治婴儿肝炎综合征并颅内出血31例,分析发病原因、诊治及预防。结果:31例肝炎综合征患儿给维生素K1、镇静、止惊、降低颅内压、保肝等治疗后,治愈19例,好转8例,自动出院3例,死亡1例。随访观察继发癫痫4例,脑性瘫痪2例。结论:颅内出血发生概率与肝功能受损程度呈正相关,故认为颅内出血与肝炎综合征有直接因果关系。而维生素K缺乏只是两者之间的一个中间环节,并非导致颅内出血的根本病因。 Objective: To analyze the clinical data of 31 children with hepatitis syndrome complicated with intracranial hemorrhage and discuss the relationship between infant hepatitis syndrome and intracranial hemorrhage. Methods: 31 cases of infantile hepatitis syndrome and intracranial hemorrhage were admitted from January 1997 to October 2007 in Dali Maternal and Child Health Hospital of Yunnan Province. The causes, diagnosis, treatment and prevention were analyzed. Results: 31 children with hepatitis syndrome were treated with vitamin K1, sedative, stop-shock, intracranial pressure reduction and liver protection. Among them, 19 cases were cured, 8 cases improved, 3 cases were discharged automatically and 1 case died. Follow-up observation of 4 cases of secondary epilepsy, cerebral palsy in 2 cases. Conclusion: The incidence of intracranial hemorrhage is positively correlated with the extent of impaired liver function. Therefore, it is considered that there is a direct causal relationship between intracranial hemorrhage and hepatitis syndrome. The lack of vitamin K is only an intermediate link between the two, is not the fundamental cause of intracranial hemorrhage.