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正常人和动物血液游离氨基酸的质和量保持恒定,取决于从组织和消化道进来的氨基酸的质和量。血液氨基酸是保证合成结构蛋白物、免疫球蛋白、蛋白类素素和酶等的重要原料。破坏血液游离氨基酸的体内平衡,可能使病程复杂化,并成为导致新的病理过程的原因。在中毒、慢性肝炎、癌症、胃炎及胃溃疡、皮肤病、营养不良等疾病时,血液游离氨基酸组成在质和量方面均有实质性变化。在各种传染病和寄生虫病时,如流脑、结核、流行性肝炎等,血液游离氨基酸的含量,其变化更为显著。各种感染时,破坏氨基酸体内平衡的病理环节,是由于肝肾功能损伤,参与氨基酸代谢的酶系破分解,组织蛋白降解加强,肠道氨基酸吸收过程发生变化等等。机体这些反应,也可能出现于各种各样的包括非传染性的病理
The quality and quantity of free amino acids in the blood of normal people and animals are kept constant, depending on the quality and quantity of amino acids coming in from tissues and digestive tracts. Blood amino acid is an important raw material to ensure the synthesis of structural proteins, immunoglobulins, protein and other enzymes. Disrupting the homeostasis of free amino acids in the blood can complicate the course and become the cause of new pathological processes. In the poisoning, chronic hepatitis, cancer, gastritis and gastric ulcer, skin diseases, malnutrition and other diseases, the blood free amino acid composition in the quality and quantity have substantial changes. In a variety of infectious diseases and parasitic diseases, such as meningitis, tuberculosis, epidemic hepatitis, blood free amino acids, the changes are more pronounced. A variety of infections, the destruction of the pathophysiology of amino acid homeostasis is due to liver and kidney dysfunction, enzymes involved in amino acid metabolism broken down, enhanced degradation of tissue proteins, intestinal amino acid absorption process changes and so on. The body’s response to these reactions can also occur in a variety of non-infectious pathologies