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我院神经内科于1988年6月收治的脑梗塞病人中有6例因静滴低分子右旋糖酐注射液(以下称简低右)发生过敏反应,现报告如下。临床资料本组男4例,女2例。年龄53~66岁。入院后均经头颅CT确诊为脑梗塞患者,其中5例伴有高血压或动脉硬化症。入院后全部用低右治疗。用药前均未做过敏试验。没有配用其他药物。发生过敏反应与用药次数的关系为:首次2例,3次1例,4次2例,5次1例。给药速度30~40滴/分。出现过敏反应的时间,最短者为用药后10分钟,化长者为30分钟。主要临床表现为:头晕(3例),胸闷(2例),恶心、呕吐(5例),畏寒,发热(6例)、休克(1例)。全部病例
In our department of neurology in June 1988 admitted to the cerebral infarction in 6 patients due to intravenous infusion of low molecular weight dextran injection (hereinafter referred to as the right lower) anaphylactic reactions are reported as follows. Clinical data The group of 4 males and 2 females. Age 53 to 66 years old. All patients were diagnosed as cerebral infarction by CT after admission. Among them, 5 patients had hypertension or arteriosclerosis. After admission, all with low right treatment. Have not done allergy test before treatment. No other drugs used. The occurrence of allergic reactions and the number of medication for the first time: 2 cases, 3 times in 1 case, 4 times in 2 cases, 5 times in 1 case. Administration rate of 30 to 40 drops / min. Allergic reaction time, the shortest for 10 minutes after treatment, the elderly for 30 minutes. The main clinical manifestations were: dizziness (3 cases), chest tightness (2 cases), nausea and vomiting (5 cases), chills, fever (6 cases) and shock (1 case). All cases