早在 195 8年 ,Kearns等〔1〕报道了 2例有视网膜色素变性、眼外肌麻痹以及完全性心脏传导阻滞的患者 ,当时 ,他们认为这是一种不常见的综合征。196 5年 ,Kearns〔2〕又报道了 9例 ,这些患者除了上述临床特点之外 ,还有一些其他的临床特征如面部、咽部、躯干和四肢的肌力弱 ,耳 As early as 1958, Kearns et al. [1] reported two patients with retinitis pigmentosa, extraocular muscle paralysis and complete heart block, when they considered it an uncommon syndrome. In 1965, Kearns [2] reported another 9 patients who, in addition to the above clinical features, had some other clinical features such as weakness of the face, pharynx, trunk and limbs,