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目的了解北京市东城区1～12岁健康儿童流感嗜血杆菌携带状况。方法选取北京市东城区1～12岁健康儿童221名,每季度采集鼻咽拭子标本1次,进行流感嗜血杆菌培养、血清分型及耐药性检测。结果东城区1～12岁健康儿童流感嗜血杆菌分离率为8.75%,累计携带率为29.41%,b型流感嗜血杆菌结合疫苗接种率为5.24%。结论 1～12岁儿童存在着一定流感嗜血杆菌疾病的风险,有必要建立科学的监测体系,研制出适合国情的流感嗜血杆菌疫苗。
Objective To understand the carrying status of Haemophilus influenzae in healthy children aged 1 ~ 12 years in Dongcheng District of Beijing. Methods Totally 221 healthy children aged 1 ~ 12 years old were selected from Dongcheng District, Beijing. Nasopharyngeal swab specimens were collected once a quarter for Haemophilus influenzae culture, serotyping and drug resistance test. Results The isolation rate of Haemophilus influenzae in healthy children aged from 1 to 12 years in Dongcheng District was 8.75%, the cumulative carrying rate was 29.41%, and the rate of Haemophilus influenzae type b conjugate vaccination was 5.24%. Conclusions There is a certain risk of Haemophilus influenzae in children aged 1 to 12 years. It is necessary to establish a scientific monitoring system and develop a Haemophilus influenzae vaccine suitable for the national conditions.