目的：探讨检测孕妇妊娠中晚期的甲状腺激素水平对评估新生儿身体发育状况的价值。方法将86例孕妇妊娠中晚期中孕周≥28周的孕妇设为观察组，＜28周的孕妇设为对照组，检测产前产后两组游离三碘甲状腺素、游离四碘甲状腺素、促甲状腺激素、总三碘甲状腺原氨酸、总甲状腺素，并比较产后两组胎儿不良事件发生率。结果产前观察组游离三碘甲状腺素、游离四碘甲状腺素、促甲状腺激素水平显著低于对照组（P＜0．01），总三碘甲状腺原氨酸、总甲状腺素水平显著高于对照组（P＜0．01）；产后两组各项指标水平比较差异均无显著性（P＞0．05）。观察组甲状腺激素水平异常发生率为83．7％、产后不良事件发生率为39．5％，对照组分别为46．5％、18．6％，观察组均显著高于对照组（ P＜0．05或0．01）。结论检测孕妇妊娠中晚期甲状腺激素水平变化对评估新生儿身体发育状况具有较高的价值，值得在临床推广应用。“,”Objective To explore the value of thyroid hormone detection in middle and late pregnant woman to estimate newborn physical development condition .Methods Of 86 middle and late pregnant women ones with gestational weeks ≥ 28 were assigned to observation group and < 28 to control group , FT3 ,FT4 ,TSH ,TT3 and TT4 were detected before and after labor ,inter‐group incidences of postnatal adverse events compared .Results Prenatal FT3 ,FT4 and TSH were significantly lower (P<0 .01)and TT3 and TT4 higher (P0 .05) .The incidences of thyroid hormone abnormality and postna‐tal adverse events were respectively 83 .7% and 39 .5% in observation and 46 .5% and 18 .6% in control group ,the former significantly higher than the latter (P<0 .05 or 0 .01) .Conclusion Thyroid hormone detections in middle and late pregnant women have higher value to estimate newborn physical development conditions ,deserves clinical generalization and application .