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目的:研究在缺血性脑血管病治疗中应用辛伐他汀与阿司匹林联合疗法的临床效果。方法:选择随机数字表法将从2015年3月至2016年3月期间本院收治的64例缺血性脑血管病患者随机分为参照组(n=32例)与实验组(n=32例),将实行阿司匹林单独治疗患者作为参照组,将实行辛伐他汀与阿司匹林联合治疗患者作为实验组,对比两组患者的临床治疗有效率以及1年后随访结果。结果:实验组缺血性脑血管病患者临床治疗总有效率以及随访1年之后心肌梗死、脑梗死发生率对比参照组数据P<0.05,差异有统计学意义。缺血性脑血管病患者随访1年之后两组在心肌梗死、脑梗死发生率方面P>0.05,差异无统计学意义。结论:将用辛伐他汀与阿司匹林联合疗法应用在缺血性脑血管病治疗中疗效显著,对于改善患者生存质量十分重要。
Objective: To study the clinical effect of simvastatin combined with aspirin in the treatment of ischemic cerebrovascular disease. Methods: Sixty-four patients with ischemic cerebrovascular disease admitted to our hospital from March 2015 to March 2016 were randomly divided into control group (n = 32) and experimental group (n = 32) Cases), aspirin monotherapy patients as the reference group, the combination of simvastatin and aspirin patients as the experimental group, compared the clinical efficacy of the two groups of patients and follow-up results after 1 year. Results: The total effective rate of clinical treatment in patients with ischemic cerebrovascular disease in experimental group and the incidence of myocardial infarction and cerebral infarction after one year of follow-up were significantly lower than those in the reference group (P <0.05). The difference was statistically significant. One year after follow-up of patients with ischemic cerebrovascular disease, there was no significant difference between the two groups in the incidence of myocardial infarction and cerebral infarction (P> 0.05). Conclusion: Simvastatin and aspirin combination therapy in the treatment of ischemic cerebrovascular disease significant effect, to improve the quality of life of patients is very important.