论文部分内容阅读
目的探讨桂枝茯苓胶囊辅助治疗异位妊娠的临床疗效。方法选取2014年6月至2016年1月我院收治的78例异位妊娠患者作为研究对象,随机分为对照组和研究组各39例,对照组给予甲氨蝶呤和米非司酮治疗,研究组则在对照组的基础上给予桂枝茯苓胶囊治疗,比较两组患者治疗前和治疗7 d后血人绒毛膜促进线激素β(β-HCG)水平和包块大小的变化,记录两组患者血β-HCG复常时间、住院时间和不良反应发生情况。结果研究组患者治疗的总有效率(89.74%)显著高于对照组(71.79%),差异有统计学意义(P<0.05);研究组患者治疗7 d后血β-HCG水平为(825.45±182.37)IU/L,显著低于对照组的(1 187.87±196.72)IU/L,差异有统计学意义(P<0.05);研究组患者治疗7 d后包块大小为(2.48±1.02)cm,显著低于对照组的(3.04±1.08)cm,差异有统计学意义(P<0.05);研究组患者血β-HCG复常时间和住院时间分别为(11.24±5.42)和(14.28±2.43)d,显著低于对照组的(17.96±5.76)和(20.13±3.16)d,差异有统计意义(P<0.05);两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论桂枝茯苓胶囊辅助常规西药治疗可有效改善异位妊娠患者的临床症状,安全有效,可应用于临床。
Objective To investigate the clinical efficacy of Guizhi Fuling Capsule in the treatment of ectopic pregnancy. Methods A total of 78 patients with ectopic pregnancy admitted to our hospital from June 2014 to January 2016 were randomly divided into control group and study group, 39 cases each. Patients in control group were treated with methotrexate and mifepristone , The study group was given Guizhifuling capsule on the basis of the control group. The changes of blood chorionic gonadotropin-β (β-HCG) level and mass size of the two groups before and 7 days after treatment were compared and recorded Two groups of patients with blood β-HCG recovery time, hospital stay and adverse reactions. Results The total effective rate (89.74%) in study group was significantly higher than that in control group (71.79%), the difference was statistically significant (P <0.05); The level of β-HCG in study group was (825.45 ± 182.37) IU / L was significantly lower than that of the control group (1 187.87 ± 196.72) IU / L, the difference was statistically significant (P <0.05); The size of the mass of the study group was (2.48 ± 1.02) cm , Which was significantly lower than that of the control group (3.04 ± 1.08 cm) (P <0.05). The mean duration of blood β-HCG recovery and hospital stay in the study group were (11.24 ± 5.42) and (14.28 ± 2.43 ) d, which was significantly lower than that of the control group (17.96 ± 5.76) and (20.13 ± 3.16) d, respectively (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05 ). Conclusion Guizhi Fuling capsule assisted conventional western medicine can effectively improve the clinical symptoms of patients with ectopic pregnancy, safe and effective, and can be applied to clinical.