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Sweet综合征(急性发热性嗜中性白细胞性皮肤病)首先报导于1964年,其特征是隆起的疼痛性红色皮肤损害,发热,嗜中性白细胞增多,组织学表现为密集的多形核白细胞的皮肤浸润.全身性应用皮质类固醇则迅速好转.Matta等指出该综合征与全身疾病有关,并报道2例急性白血病.后陆续有人报道本综合征与恶性肿瘤如睾丸胚胎癌、转移性腺癌(未知原发部位)及5例急性骨髓性白血病的关系.本文报告1例Sweet综合征发病在急性骨髓性白血病之前达数月.
Sweet syndrome (acute febrile neutrophilic leukoplakia) was first reported in 1964 and was characterized by bulging painful red skin lesions, fever, neutrophilia, and histologic findings of dense polymorphonuclear leukocytes Of systemic infiltration of corticosteroids are rapidly improved.Matta pointed out that the syndrome and systemic diseases, and reported 2 cases of acute leukemia.After another reported this syndrome and malignant tumors such as testicular embryonal carcinoma, metastatic adenocarcinoma ( Unknown primary site) and 5 cases of acute myeloid leukemia.The report of 1 case of Sweet syndrome onset in acute myeloid leukemia for several months.