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目的 :评价异丙酚静脉麻醉人工流产的效应。方法 :16 0 0例ASAⅠ～Ⅱ、妊娠 1～ 3月孕妇 ,80 0例自愿实行全麻人工流产者为治疗组 ,另 80 0例自愿无麻醉人工流产者为对照组。治疗组采用两次推注给药法 ,首次给药至深镇静 ,1 5～ 2分钟后再次追加 5 0 %诱导量。观察诱导剂量、诱导过程术中HR、BP、SpO2 变化、恢复时间、副作用、患者满意程度及对照组VAS评分。结果 :两组平均手术时间为 5 2 8～ 5 44分钟 ,治疗组异丙酚用量 187 40± 32 18mg ;治疗组术中MAP下降大于 2 0 %的患者为 13 % ,对照组为 39% ;治疗组HR减慢超过 2 0 %为 7 9% ,对照组为 39% ;治疗组恶心和呕吐率分别为 2 1%和 1 9% ,对照组为 2 3 9%和 6 1% ,均有非常显著差异 (P <0 0 1)。对照组 80 1%患者出现人流综合症 ,VAS评分 7 1分 ,而治疗组满意率为 99 4% ,无不满意者 ,麻醉后清醒和定向力恢复迅速。结论 :异丙酚可满足人工流产手术的需要。异丙酚静脉麻醉用于人工流产明显减低副作用 ,患者满意率提高
Objective: To evaluate the effect of propofol intravenous anesthesia induced abortion. Methods: One hundred and sixty ASAⅠ ~ Ⅱ pregnant women from January to March of pregnancy were enrolled in this study. 80 0 cases of induced abortion were randomly selected as the treatment group and another 80 0 cases of voluntary non-anesthetic induced abortion were used as the control group. The treatment group used two bolus administration methods, the first administration to the deep sedation, 1 5 ~ 2 minutes after the additional 50% induction. The induction dose, the changes of HR, BP and SpO2, recovery time, side effects, patient satisfaction and VAS score of the control group were observed. Results: The mean operative time was 528-544 minutes in both groups. The dosage of propofol in the treatment group was 187 40 ± 32 18 mg. In the treatment group, the MAP decreased more than 20% in 13% of the patients and 39% in the control group. In the treatment group, HR decreased more than 20% to 79% and that in the control group to 39%. The nausea and vomiting rates in the treatment group were 21% and 19%, respectively, while those in the control group were 23.9% and 61% Very significant difference (P <0.01). The control group 80 1% of patients with flow syndrome, VAS score 7 1 points, while the treatment group satisfaction rate of 99 4%, no discontent, awake after anesthesia and rapid recovery of orientation. Conclusion: Propofol can meet the needs of induced abortion. Propofol intravenous anesthesia for abortion significantly reduced side effects, patient satisfaction increased