根治性前列腺切除术中盆腔淋巴结切除范围的确定需要了解淋巴结转移局部解剖学知识。小的淋巴结转移可能在标准化的组织病理学检查中很难被发现。为此,作者对接受根治性前列腺切除术+扩大盆腔淋巴结切除治疗的前列腺癌患者,联合进行了分子和组织病理学的局部解剖学绘图研究。本组包括未行新辅助疗法患者52例。扩大淋巴结切除包括闭孔窝、髂外、髂内和髂总血管范围。对直径≥3 mm的淋巴结进行定量qRT-PCR,观察PSA表达及标准化组织病理 Radical prostatectomy pelvic lymph node dissection to determine the scope of the need to understand the local anatomy of lymph node metastasis. Small lymph node metastases may be difficult to detect in a standardized histopathological examination. To this end, the authors performed a combined molecular and histopathological local anatomical mapping study of prostate cancer patients undergoing radical prostatectomy plus extended pelvic lymph node dissection. This group includes 52 patients without new adjuvant therapy. Enlarged lymph node dissection includes closed-cell, external iliac, internal iliac and iliac vessels. Quantitative qRT-PCR was performed on lymph nodes of> 3 mm in diameter to observe PSA expression and normalized histopathology