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目的观察SARS患者血清铁蛋白含量变化。方法用电化学发光法检测了66例SARS患者血清铁蛋白(Ferritin)含量,与正常对照组作了比较。结果患者铁蛋白含量明显高于对照组,重型SARS患者铁蛋白含量明显高于普通型。恢复期患者血清铁蛋白含量降低但仍高于对照组。结论SARS患者存在铁蛋白代谢异常,铁蛋白含量变化可能反映病理程度,动态检测血清铁蛋白水平有助于病情的观察。
Objective To observe the changes of serum ferritin in SARS patients. Methods The levels of Ferritin in 66 cases of SARS were detected by electrochemiluminescence method and compared with the normal control group. Results The ferritin content of patients was significantly higher than that of the control group, and the content of ferritin in patients with severe SARS was significantly higher than that of the common type. Patients with convalescent serum ferritin decreased but still higher than the control group. Conclusion The patients with SARS have abnormal ferritin metabolism. The changes of ferritin may reflect the pathological changes. The dynamic detection of serum ferritin may be helpful to the observation of the disease.