目的　观察垂体后叶素对非静脉曲张消化道出血患者的治疗效果。方法　 40例消化道出血病人经急诊胃镜排除静脉曲张确断 ,出血量均 >10 0 0ml,病因分别为消化性溃疡、急性胃黏膜病变、食管贲门黏膜撕裂综合征等。所有病例给予法莫替丁 40～ 80mg/d静点或洛赛克 40mg静推 ,每日 2次 ,2 4h后仍继续出血 ,加用垂体后叶素 0 .3～ 0 .4U/min静点维持 ,有效时 ,每 2 4h减半 ,共用 3d。结果　 2 4h内止血为显效 ,72h内止血为有效。 31例 (77.5 % )显效 ,总有效率 92 .5 % (37/ 40 ) ,3例无效。结论　垂体后叶素治疗非静脉曲张消化道出血疗效可靠 ,其副作用有腹鸣、腹痛、心悸等 ,经对症治疗 ,症状可缓解 Objective To observe the therapeutic effect of vasopressin on patients with non-variceal hemorrhage. Methods Forty cases of patients with gastrointestinal bleeding were diagnosed by gastroscopy emergency rupture of varicose veins, the amount of bleeding were> 100ml, the causes were peptic ulcer, acute gastric mucosal lesions, esophageal and gastric cardial tear syndrome. All cases given famotidine 40 ~ 80mg / d intravenous or intravenous injection of Losec 40mg, 2 times a day, 24 hours after continued bleeding, plus pituitrin 0.3 ~ 0. 4U / min static Points to maintain, effective, every 2 4 h halved, sharing 3d. Results within 24 hours of bleeding was markedly effective, within 72h to stop bleeding is effective. 31 cases (77.5%) markedly effective, the total effective rate was 92.5% (37/40), 3 cases were ineffective. Conclusion Pituitrin for the treatment of non-variceal gastrointestinal bleeding is reliable, the side effects of abdominal gas, abdominal pain, heart palpitations, symptomatic treatment, the symptoms can be alleviated