对以关节损害为首发表现的Castleman病误诊1例结合文献报告如下。1病历摘要男,63岁。诊断Castleman病5 a。患者2002-05起出现指间关节肿痛,逐渐累及双腕、掌指、双膝、双踝多个关节,多次查血沉(ESR)56~87 mm/h,C反应蛋白(CRP)7.8~9.27 mg/dl;抗核抗体(ANA)1∶80,抗“O”及类风 One case of Castleman’s disease misdiagnosed as a first manifestation of joint damage was reported in the literature as follows. A summary of medical records Male, 63 years old. Diagnosis Castleman’s disease 5 a. The patient started to have swelling of the interphalangeal joint from 2002-05, gradually involving the wrist, metacarpophalangeal, knees, multiple ankle joints, multiple echocardiography (ESR) 56-87 mm / h and CRP 7.8 ~ 9.27 mg / dl; antinuclear antibody (ANA) 1:80, anti-O and wind-like