对以红霉素为代表的大环内酯类抗生素近年在疟疾、弓形虫脑炎、放红菌病、小螺菌鼠咬热、卡他莫拉菌感染、庞克提亚热、人埃立克体病、分枝杆菌、Ｑ热肝炎、散在复发性斑疹伤寒、品他病、Ｗｈｉｐｐｌｅ病、弯曲菌病、汉赛巴尔通体病、沙眼、社区获得性肺炎、卡氏肺囊虫病、霍乱Ｏ１３９感染、ＴＳＳ、细菌生物膜病等感染性疾病中的应用与探索进行了综述。 Erythromycin, represented by macrolide antibiotics in recent years in malaria, toxoplasmosis encephalitis, erythrobotic disease, spiranitis mouse bite fever, catarrhal Mora infection, punktia fever, human Egypt Mycobacterium tuberculosis, Mycobacterium tuberculosis, Mycobacterium tuberculosis, Q Hepatitis, Respiratory recurrent typhus, Commodal disease, Whipple’s disease, Campylobacter s disease, Bartonella henselae, Trachoma, community-acquired pneumonia, , Cholera O139 infection, TSS, bacterial biofilm disease and other infectious diseases in the application and exploration are reviewed.