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全氟异丁烯（ＰＦＩＢ）是聚四氟乙烯裂解产物中毒性最大的物质，吸入中毒后主要引起特征性的通透性肺水肿，严重时导致死亡。为评价ＰＦＩＢ的急性毒性，我们采用平均致死量法测定了小鼠、大鼠和家兔３种动物的半数致死浓度ＬＣ５０。昆明种小鼠４８只，Ｗｉｓｔａｒ大鼠４０
Perfluoroisobutylene (PFIB) is the most toxic substance in the pyrolysis products of Teflon. After inhalation poisoning, it causes the characteristic permeability pulmonary edema, which leads to serious death. To assess the acute toxicity of PFIB, we used the mean lethal dose method to determine the median lethal concentration (LC50) of mice, rats and rabbits. 48 Kunming mice and 40 Wistar rats