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目的观察氨溴索的不同给药方式治疗婴幼儿下呼吸道感染的疗效。方法选择婴幼儿下呼吸道感染患儿186例,随机分为雾化组64例,静脉滴注组62例,口服组60例,临床观察三组病例咳嗽、气促、肺部体征消失情况。结果雾化组患儿的咳嗽、气促、肺部体征消失时间明显少于静脉滴注组和口服组。经统计学检验,差异有统计学意义(P<0.05)。静脉滴注组和口服组疗效差异无统计学意义。结论氨溴索雾化吸入治疗婴幼儿下呼吸道感染疗效显著,起效快,是首选给药方式。
Objective To observe the efficacy of different administrations of ambroxol in the treatment of lower respiratory tract infections in infants and young children. Methods 186 cases of infants with lower respiratory tract infection were randomly divided into atomization group (n = 64), intravenous infusion group (n = 62) and oral group (n = 60). The clinical observation of three groups of patients were cough, shortness of breath and disappearance of lung signs. Results In the atomized group, cough, shortness of breath, and disappearance of lung signs were significantly less than those in the intravenous drip group and the oral group. Statistically, the difference was statistically significant (P <0.05). There was no significant difference in the curative effect between intravenous drip group and oral group. Conclusion Ambroxol inhalation for the treatment of lower respiratory tract infection in infants and young children with significant effect, rapid onset, is the preferred mode of administration.