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新生儿缺氧缺血性脑病(HIE)是新生儿死亡的主要疾病之一。也是新生儿致残的常见原因。HIE常并发惊厥,反复的惊厥又加重脑损害。我们在综合治疗的基础上于1996年1月开始应用利多卡因止痉,取得较好效果,现介绍如下。 1 资料与方法 1.1 一般资料:28例符合1989年济南全国儿科会议HIE临床诊断和分度,男19例,女9例;日龄1/2小时~5天,平均3±1.2天;重度窒息21例,中度窒息7例。全部病例有不同程度的惊厥发作。
Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the major diseases of neonatal death. It is also a common cause of disability in newborns. HIE often complicated by convulsions, repeated convulsions and increase brain damage. On the basis of comprehensive treatment, we started to apply lidocaine to stop spasticity in January 1996 and achieved good results. Now we introduce the following. 1 Materials and Methods 1.1 General Information: 28 cases in line with the 1989 Jinan National Pediatric HIE clinical diagnosis and classification, 19 males and 9 females; day of age 1/2 hours to 5 days, an average of 3 ± 1.2 days; severe asphyxia 21 cases, 7 cases of moderate asphyxia. All cases have varying degrees of seizures.