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以≤10mW·cm~(-2)的2450MHz微波照射健康成年雄性小鼠,观察骨髓PCE微核检出率及附睾精子畸变率。急性试验5—10mW·cm~(-2)剂量组精子畸变率显著增高,相关回归分析有随剂量增大而增高的趋势。畸变各型精子中以尾折叠型为主,约占1/2。表明5—10mW·cm~(-2)微波急性辐照对精子形态学转变过程有一定影响。亚急性试验停止辐照4天后,发现精子畸形减少,与阴性组无差异。提示该剂量下微波辐照引起生殖细胞损伤属可逆性,机体的代偿修复能力对较轻的畸变在短期内可使之修复。急性、亚急性辐照后小鼠PCE微核检出率均在正常范围。表明在有效控制辐照剂量条件下,10mW·cm~(-2)微波SB不足以引起微核率的增高。从监测微波剂量对机体损伤角度探讨,微核试验不宜作为卫生标准衡量的敏感指标。
Healthy adult male mice were irradiated with 2450MHz microwave at ≤10mW · cm -2, and the detection rate of PCE micronuclei and the rate of epididymal sperm defect were observed. Acute experimental 5-10mW · cm ~ (-2) dose group sperm aberration rate was significantly increased, the correlation regression analysis with the increase of dose tends to increase. Distortion of various types of sperm in the tail fold-based, accounting for about 1/2. The results showed that the acute radiation with 5-10mW · cm ~ (-2) had some influence on the morphological transformation of sperm. Subacute trials stopped irradiation 4 days after the sperm deformity was found to be reduced, no difference with the negative group. Prompted that the dose of radiation caused by germ cell damage is reversible, the body’s ability to compensate for the repair of the lighter distortion in the short term can make it repair. The detection rates of PCE micronuclei in mice after acute and subacute irradiation were within the normal range. The results showed that under the effective control of irradiation dose, 10mW · cm ~ (-2) microwave SB was not enough to cause the increase of micronucleus rate. From the perspective of monitoring the dose of microwave damage to the body, micronucleus test should not be used as a sensitive indicator of health standards.