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急性中毒性脑病系指在短时间内大量毒物迅速进入人体,引起中枢神经系统严重器质性和功能性损害的一组临床表现。它见于重度急性中毒,也可以是急性中毒的迟发表现。 (一)病因 引起急性中毒性脑病的毒物很多,根据发病机理可分以下几方面。 1.亲神经毒物:这类毒物通过干扰神经组织代谢或抑制酶活性而损及中枢神经系统。 (1)金属与类金属:铅、铊、四乙基铅、三乙基锡、硼烷; (2)溶剂类:苯、甲苯、二甲苯、汽油、甲醇、乙醇、三氯乙烯、二硫化碳、氯甲烷、二氯乙烷、环氧乙烷;
Acute toxic encephalopathy refers to a large number of toxins in a short time quickly into the body, causing serious central nervous system organic and functional impairment of a group of clinical manifestations. It is seen in severe acute poisoning, it can also be a delayed manifestation of acute poisoning. (A) cause Acute toxic encephalopathy many toxic, according to the pathogenesis can be divided into the following aspects. 1. Pro-nerve poison: This poison through the interference of nerve tissue metabolism or inhibit the activity of the enzyme and the central nervous system. (2) Solvents: benzene, toluene, xylene, gasoline, methanol, ethanol, trichlorethylene, carbon disulfide, Chloromethane, Dichloroethane, Ethylene oxide;