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目的观察升降散加减辅助治疗小儿猩红热的临床疗效。方法 66例猩红热患儿按随机数字表法分为治疗组和对照组,各33例。2组均给予西医常规抗感染及对症治疗,治疗组加用升降散加减口服。治疗1周后比较2组患儿的临床症状、体征改善时间,白细胞计数、C反应蛋白(CRP)指标变化。结果治疗组总有效率(93.9%)显著高于对照组(75.8%),差异有统计意义(P<0.05)。治疗组患儿平均退热时间、咽痛消失时间均显著短于对照组,差异均有高度统计意义(P<0.01);2组皮疹消退时间比较,差异无统计意义(P>0.05)。与同组治疗前比较,治疗后2组白细胞计数和CRP水平均显著降低,差异均有高度统计意义(P<0.01);治疗后,治疗组白细胞计数和CRP水平均显著低于对照组,差异均有高度统计意义(P<0.01)。结论升降散加减在改善小儿猩红热的临床症状、体征、实验室指标等方面疗效显著,值得临床推广应用。
Objective To observe the clinical effects of Shengjiang Powder in the treatment of pediatric scarlet fever. Methods 66 cases of scarlet fever were divided into treatment group and control group according to random number table method, with 33 cases in each group. Both groups were given routine anti-infectives and symptomatic treatment of Western medicine, the treatment group plus oral plus or minus oral. After 1 week of treatment, clinical symptoms, signs of improvement, white blood cell count and C-reactive protein (CRP) were compared between the two groups. Results The total effective rate (93.9%) in the treatment group was significantly higher than that in the control group (75.8%), the difference was statistically significant (P <0.05). The treatment group, the average time of antipyretic fever, sore throat disappeared significantly shorter than the control group, the differences were highly statistically significant (P <0.01); 2 rash subsided time, the difference was not statistically significant (P> 0.05). Compared with the same group before treatment, the white blood cell count and CRP level in the two groups were significantly decreased after treatment, the differences were statistically significant (P <0.01); After treatment, the treatment group, the white blood cell count and CRP levels were significantly lower than the control group, the difference All were highly statistically significant (P <0.01). Conclusion Shengsan San addition and subtraction in the treatment of scarlet fever in children to improve the clinical symptoms, signs, laboratory indicators such as significant effect, worthy of clinical application.