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本文分析了35例亚急性重症肝炎(简称亚重肝)的超微结构改变。其中病因有 HBV 32例(91.4%),NANB 1例(2.9%),HBV 合并 HDV1例(2.9%),未定2例。早期4例(11.4%),中期24例(68、6%),后期7例(20%)。电镜下见大片肝细胞坏死,为炎症细胞取代,残存及再生肝细胞均呈不同程度的变性,浆内出现灶性及融合性液化区,细胞器严重损害,尤以线粒体及内质网为甚,作者认为光镜和电镜结合观察,是研究亚重肝形态改变的重要手段。
This article analyzes the ultrastructural changes in 35 cases of subacute severe hepatitis (sub-heavy liver). Among them, 32 were HBV (91.4%), 1 was NANB (2.9%), 1 was HBV (2.9%) and 2 were undetermined. 4 cases (11.4%) were early stage, 24 cases (68.6%) were mid-stage and 7 cases (20%) were late stage. Electron microscope, see a large piece of liver cell necrosis, replaced by inflammatory cells, residual and regenerative liver cells were varying degrees of degeneration, the pulp appeared focal and fusion liquefaction zone, organelles serious damage, especially mitochondria and endoplasmic reticulum is even worse, The authors believe that the combination of light microscopy and electron microscopy observation is an important means to study the morphological changes of sub-heavy liver.