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成人Still氏病(Adult Onset still’s disease,AOSD)是一种血清阴性多关节炎。1987年以前我国多称为“变应性亚败血症”,认为系罕见疾病,近年临床报道日益增多,可能与临床医师对本病的认识提高有关。本文报告8例AOSD,并就其临床特点作一些分析。 1 临床资料 1.1 一般资料 AOSD共8例,女7例,男1例,年龄18～60岁,平均35岁。入院前病程1周～5年,1个月以上者5例。 1.2 临床表现 8例皆有发热、皮疹。7例有咽痛、关节痛。浅表淋巴结肿大4例,肝大3例,脾大1例。病程中出现肝功能异常3例,肾功能异常1例。胸
Adult Onset still’s disease (AOSD) is a seronegative polyarthritis. Before 1987, many of our country called “allergic sub-sepsis”, that Department of rare diseases, increasing clinical coverage in recent years, may be related to clinicians to improve awareness of the disease. This article reports 8 cases of AOSD, and some of its clinical features for some analysis. 1 Clinical data 1.1 General Information AOSD a total of 8 cases, 7 females, 1 male, aged 18 to 60 years, mean 35 years. Pre-admission course of 1 week ~ 5 years, 1 month or more in 5 cases. 1.2 Clinical manifestations of 8 cases all have fever, rash. 7 cases of sore throat, joint pain. Superficial lymph nodes in 4 cases, 3 cases of hepatomegaly, splenomegaly in 1 case. Liver disease in the course of abnormalities in 3 cases, 1 case of renal dysfunction. chest