布氏菌噬菌体在60年代仅有一个 Tb 株,70年代后,迄今得到10余株较有价值的代表株。特别是 Douglas 得到 AK_2株,它是一个广谱噬菌体,这对噬菌体的分群,及其在布氏菌属中的鉴别和分类可起重要作用。但 R 型噬菌体效价低、活性不够稳定,需要进一步改进提高。S 型各群噬菌体特异性较强,效价较高,对与布氏菌有共同抗原的属外菌种均不裂解;对属内菌株 In the 1960s, only one strain of Tb was found in the bacteriophages of B.brevis. More than 10 strains of representative strains have been obtained since the 1970s. In particular, Douglas obtained the AK_2 strain, which is a broad-spectrum phage that can play an important role in the clustering of phages and their identification and classification in the genus Brucella. However, the low titer of phage type R, the activity is not stable enough, need to be further improved and improved. The S-type phage showed strong specificity and high titer, and did not lyse the genera that belong to the genus Brucella that had the common antigen.