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目的 :探讨蛋白 S在脑梗死中的改变。方法 :脑梗死患者 42例 ,健康体检者 40例作为对照。使用自动凝血仪检测蛋白 S活性 ,EL ISA法检测总和游离蛋白 S抗原含量。结果 :42例脑梗死患者中检出 7例蛋白 S活性缺乏 ,其中仅有 2例伴有游离蛋白 S抗原严重下降。结论 :脑梗死中存在蛋白 S活性缺乏 ,但并不与游离蛋白 S抗原下降相平行
Objective: To investigate the changes of protein S in cerebral infarction. Methods: Forty-two patients with cerebral infarction and 40 healthy subjects were used as control. The activity of protein S was detected by automatic coagulation analyzer, and the content of free S protein was detected by ELISA. RESULTS: Seven of 42 patients with cerebral infarction were found to be deficient in protein S activity, of which only 2 were associated with a severe decrease in free protein S antigen. Conclusion: There is a lack of protein S activity in cerebral infarction, but it is not parallel to the decline of free protein S antigen