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目的:探讨颈动脉内中膜厚度(CIMT)与无症状脑梗死(SCI)的相关性。方法:回顾性分析1008例健康体检患者的临床资料,并分为2型糖尿病组和非糖尿病组,用单因素和多因素回归法分析两组患者CIMT与SCI的相关性。结果:2型糖尿病组患者合并SCI的比例明显高于非糖尿病组患者(44.1%vs29.1%),虽然两组合并SCI患者CIMT均明显高于不合并SCI者(P<0.01),但多因素Logistic回归分析仅在2型糖尿病组患者中发现CIMT是SCI的独立危险因素(OR=1.96,95%CI1.00～3.86,P=0.03)。结论:2型糖尿病患者CIMT是SCI的独立危险因素。
Objective: To investigate the relationship between carotid intima-media thickness (CIMT) and asymptomatic cerebral infarction (SCI). Methods: The clinical data of 1008 healthy people were retrospectively analyzed. The data were divided into type 2 diabetes group and non-diabetes group. The correlation between CIMT and SCI was analyzed by univariate and multivariate regression analysis. Results: The proportion of patients with type 2 diabetes mellitus complicated with SCI was significantly higher than that of non-diabetic patients (44.1% vs 29.1%). Although the CIMT was significantly higher in both groups with SCI than those without SCI (P <0.01) Logistic regression analysis revealed that CIMT was an independent risk factor for SCI only in type 2 diabetic patients (OR = 1.96, 95% CI 1.00-3.86, P = 0.03). Conclusion: CIMT in type 2 diabetic patients is an independent risk factor for SCI.