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目的探讨灌注化疗对胰腺癌的治疗效果,以及与其它方法联合综合治疗的效果。方法采用Seldinger技术经股动脉插管胰腺供血动脉内灌注化疗药物,经皮肝穿刺进行外引流或植入胆道支架进行内引流解除黄疸。结果21例病人疼痛症状达到CR水平,有24例病人肿瘤体积未见明显变化,行PTBD病人黄疸完全解除。结论动脉灌注化疗对缓解肿瘤生长速度和减少疼痛是一种可选择的有效方法,但对减少肿瘤体积、改善黄疸疗效有限,可以在一定程度上改善症状,延长病人生存期。
Objective To investigate the therapeutic effect of perfusion chemotherapy on pancreatic cancer and the effect of combination therapy with other methods. Methods The Seldinger technique was used to perfuse chemotherapeutic drugs through the femoral arterial cannulation pancreas and percutaneous liver puncture for external drainage or implantation of biliary stents for internal drainage to relieve jaundice. Results The pain symptoms of 21 patients reached the level of CR, 24 patients had no significant changes in tumor volume, patients with PTBD jaundice completely lifted. Conclusion Arterial infusion chemotherapy is an effective and effective method to relieve tumor growth and reduce pain. However, it has limited curative effect on reducing tumor volume and improving jaundice, and can ameliorate symptoms and extend patient survival.