CMF方案用于胃肠道肿瘤术后化疗(附42例报告)

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胃肠道恶性肿瘤的治疗,目前仍以手术根治为主要治疗手段,治疗效果尚佳,但难以彻底治愈,大部分患者术后2~3年内复发.近年来,术后联合化疗及辅助联合化疗的应用,有效地弥补了外科手术之不足,大大地提高了治愈率,减少和延缓了肿瘤复发.1989年以来,我们采用CMF方案加扶正中药对42例胃肠道恶性肿瘤患者进行了术后联后化疗(腺癌36例、粘液腺癌6例),收到了满意效果,总有效率达88.1%(37/42).曾对3例接受术后化疗患者进行了二次剖腹探查,证实切除原发病灶后,化疗可使转移灶完全消失;另外,采用B超、CT等辅助检查手段,对其它接受术后化疗患者进行了检测,结果亦证实了化疗的作用.同时,内服扶正中药可明显的提高疗效、减少化疗药物的毒副反应.此方案疗效可靠,使用方便、安全、毒副反应小,适于在基层医院推广应用. The treatment of gastrointestinal malignant tumors is still based on surgical radical treatment as the main treatment, the treatment effect is good, but it is difficult to completely cure, most of the patients relapse within 2 to 3 years. In recent years, postoperative combined chemotherapy and adjuvant chemotherapy The application effectively compensates for the lack of surgery, greatly improves the cure rate, and reduces and delays the recurrence of tumors. Since 1989, we have used the CMF regimen plus Fuzheng Chinese medicine for 42 patients with gastrointestinal cancer after surgery. Post-concomitant chemotherapy (adenocarcinoma 36 cases, mucinous adenocarcinoma 6 cases), received a satisfactory effect, the total effective rate of 88.1% (37/42). 3 cases of patients undergoing chemotherapy after undergoing a second laparotomy, confirmed After resection of the primary lesion, chemotherapy can completely eliminate the metastases; in addition, the use of B-ultrasound, CT and other auxiliary examination methods, other patients undergoing postoperative chemotherapy were tested, the results also confirmed the role of chemotherapy. At the same time, oral administration of Chinese medicine Can significantly improve the efficacy, reduce the toxicity of chemotherapy drugs. This program is reliable, easy to use, safe, toxic side effects, suitable for promotion and application in basic hospitals.
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期刊
原发性小肠肿瘤较少见。因小肠的解剖生理特点,早期缺乏典型症状和体征,亦无特殊检查方法,诊断颇为困难。现将我们1984~1995年收治的43例小肠肿瘤予以总结,对其诊断治疗加以