本研究报告了不属于种族色素表征,也不与全身疾病或综合征有关的口腔粘膜褐色或黑色的色素沉着斑105例。多数情况下黑色素沉着斑是孤立的损害。最常见于唇红缘,其次是牙龈和颊粘膜。临床显示色素沉着并呈斑状。其最大直径为0.1～0.3厘米。患者的平均年龄为41岁,女与男之比为2.2:1。多数病员是白种人(82％),其余的 This study reported 105 cases of brown or black pigmented plaques in the oral mucosa that were not characterized by ethnic pigments or associated with systemic disease or syndrome. In most cases melanin pigmentation is an isolated lesion. The most common is the vermilion margin, followed by gums and buccal mucosa. Clinical manifestations of pigmentation and patchy. Its maximum diameter is 0.1 to 0.3 cm. The average age of the patients was 41 years and the ratio of women to men was 2.2:1. Most of the patients were white (82%), the rest