转位分子蛋白(TSPO)是线粒体渗透性转运孔(MPTP)的主要组成部分之一,参与了由线粒体诱导的细胞凋亡过程。作为临床上治疗较棘手的胶质瘤,如何能以此为基础,获得较其它治疗方法更好的治疗效果,已得到了一些神经外科医师和基础科研人员的关注,并且已作了和TSPO相关的体外药物方面的研究。本文对胶质瘤细胞中TSPO蛋白与细胞凋亡的关系进行综述。 Translocated molecular protein (TSPO) is one of the major components of mitochondrial permeability transition pore (MPTP) and is involved in mitochondria-induced apoptosis. As a clinically treatable intractable glioma, how to get a better therapeutic effect than other treatments based on it has attracted the attention of some neurosurgeons and basic researchers, and has been related to TSPO In vitro drug research. This article reviews the relationship between TSPO protein and apoptosis in glioma cells.