研究表明,肿瘤的生长是无序的生长,血管生成不充分,所以人体实体瘤大多存在氧缺乏区域,这一区域的肿瘤细胞抵抗电离辐射的能力超过含氧量正常的肿瘤细胞的2～3倍,其主要原因是减少了氧自由基对DNA增殖的损伤[1]。实体瘤乏氧是放疗失败的主要原因,克服乏氧所导致的放疗抵抗是提 Studies have shown that tumor growth is disorderly growth, insufficient angiogenesis, so most of the human solid tumors exist oxygen-deficient areas, the ability of tumor cells in this area to resist ionizing radiation than normal oxygen-containing tumor cells 2 to 3 Times, the main reason is to reduce the oxygen free radicals on DNA damage [1]. Hypoxia of solid tumors is the main reason for the failure of radiotherapy, to overcome the hypoxia caused by radiation resistance is to mention