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卵巢性索间质肿瘤约占卵巢良性肿瘤的4%,恶性肿瘤的7%。组织学表现多种多样,有时仅靠普通的HE染色,很难与卵巢其他良、恶性肿瘤鉴别。例如:Sertoli-Leydig细胞瘤和粒层细胞瘤与卵巢的子宫内膜样腺癌的鉴别;幼年型粒层细胞瘤与卵巢高钙型小细胞癌的鉴别;肉瘤型粒层细胞瘤与血管肉瘤等间叶性肉瘤的鉴别;以及与子宫内膜间质肉瘤、未分化癌、类癌、促纤维增生性小细胞癌、Brenner、生殖细胞肿瘤的鉴别。以往,由于缺乏特异性较强的生物学标志物,而免疫组化在卵巢性索间质肿瘤的诊断和鉴
Ovarian sex cord stromal tumors account for about 4% of ovarian benign tumors, 7% of malignant tumors. Histological manifestations varied, sometimes only by ordinary HE staining, it is difficult to identify with other ovarian benign and malignant tumors. For example: Sertoli-Leydig cell tumor and granulosa cell tumor and ovarian endometrial adenocarcinoma; juvenile granulosa cell tumor and ovarian calcification of small cell carcinoma of the differential; sarcoma and angiosarcoma Identification of isofacial sarcomas; and identification of endometrial stromal sarcoma, undifferentiated carcinoma, carcinoid, fibrotic proliferative small cell carcinoma, Brenner, germ cell tumors. In the past, due to the lack of specific biological markers, immunohistochemistry in the diagnosis and diagnosis of ovarian sex cord tumors