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为探讨分泌型脑膜瘤的病理形态学及超微结构特征,对此型脑膜瘤19例进行临床病理、免疫组化及超微结构观察。结果表明,肿瘤细胞胞质内可见大小不等均匀一致的嗜酸性透明状包涵体,PAS和阿尔辛蓝染色阳性,电镜观察发现此包涵体为瘤细胞胞质内的微腺泡的腔内分泌物。结论:免疫组化染色及超微结构观察对分泌型脑膜瘤的诊断及鉴别诊断具有重要意义。
To explore the pathological morphology and ultrastructural features of secretory meningiomas, 19 cases of this type of meningioma were observed with clinicopathological features, immunohistochemistry and ultrastructure. The results showed that the eosinophilic transparent inclusions with uniform size ranging from cytoplasm to cytoplasm could be seen in the cytoplasm of tumor cells. PAS and Alcian blue staining were positive. Electron microscopy showed that this inclusion body was the cavity secreted by the cytoplasm of tumor cells . Conclusion: The immunohistochemical staining and ultrastructure observation are of great significance for the diagnosis and differential diagnosis of secretory meningioma.