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目的探讨糖尿病患者发生急性冠状动脉综合征后行冠状动脉介入治疗同预后的关系。方法选择本院治疗的急性冠状动脉综合征行介入治疗的患者200例,根据患者是否合并糖尿病分为观察组和对照组,观察组患者合并糖尿病,对照组患者未合并糖尿病,在介入治疗后对患者进行随访,观察患者治疗结果。结果观察组患者支架再狭窄发生率、非致死性心肌梗死发生率均高于对照组,经统计学分析比较,差异有统计学意义(P<0.05)。两组患者心绞痛复发和全因性死亡率比较经统计学分析差异无统计学意义(P>0.05)。结论糖尿病患者行冠状动脉介入治疗后发生支架再狭窄、非致死性心肌梗死发生率均高于对照组,提示糖尿病患者冠状动脉支架内再狭窄发生率高,与糖尿病患者内膜过度增生等相关,糖尿病患者非致死性心肌梗死发生率高,与糖尿病患者冠状动脉广泛严重动脉粥样硬化、冠状动脉血管弥漫病变相关。积极地控制糖尿病患者血糖能够减少介入治疗后冠状动脉不良事件的发生,对患者预后具有重要意义。
Objective To investigate the relationship between coronary intervention and prognosis in patients with diabetes mellitus after acute coronary syndrome. Methods 200 patients with acute coronary syndrome treated by our hospital were divided into observation group and control group according to whether patients with diabetes mellitus were combined or not. Patients in observation group had diabetes mellitus, and patients in control group did not have diabetes mellitus. After interventional therapy Patients were followed up to observe the results of patient treatment. Results The incidence of stent restenosis and non-fatal myocardial infarction in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P <0.05). Two groups of patients with angina relapse and all-cause mortality compared with the statistical analysis showed no significant difference (P> 0.05). Conclusion The incidence of stent restenosis and non-fatal myocardial infarction in patients with diabetes mellitus after coronary intervention is higher than that in control group, which indicates that the incidence of coronary in-stent restenosis is high in patients with diabetes mellitus, which is associated with intimal hyperplasia in diabetic patients, Diabetic patients with high incidence of non-fatal myocardial infarction, coronary atherosclerosis with extensive coronary atherosclerosis, coronary artery diffuse lesions related. Active control of blood glucose in diabetic patients can reduce the occurrence of coronary artery adverse events after interventional therapy, which is of great significance to the prognosis of patients.