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目的探讨90Y-玻璃微球介入治疗晚期恶性肿瘤的疗效。方法共18例恶性肿瘤病人,其中肝癌6例,肺癌5例,颈部淋巴结转移癌5例,上颌窦癌1例,肺癌胸壁转移1例,均经病理诊断证实。采取直接注入或者利用B超和CT引导下将90Y-玻璃微球引入肿瘤组织。结果 18例肿瘤中,完全消失(CR)为2例,部分缩小(PR)为9例,肿瘤稳定(SD)为6例,肿瘤进展(PD)为1例。14例病人可见疼痛减轻,4例疼痛未见明显缓解。结论本方法可在晚期恶性肿瘤治疗上发挥重要作用,有较大临床应用前景。
Objective To investigate the efficacy of 90Y-glass microsphere interventional therapy for advanced malignancies. Methods A total of 18 cases of malignant tumor patients, including 6 cases of liver cancer, 5 cases of lung cancer, cervical lymph node metastasis in 5 cases, 1 case of maxillary sinus cancer, lung cancer in 1 case of chest wall metastasis were confirmed by pathological diagnosis. Take 90Y-glass microspheres into the tumor tissue by direct injection or under the guidance of B-ultrasound and CT. Results Of the 18 tumors, there were 2 cases of complete disappearance (CR), 9 cases of partial reduction (PR), 6 cases of stable tumor (SD) and 1 case of tumor progression (PD). Pain was relieved in 14 patients and no pain was relieved in 4 patients. Conclusion This method can play an important role in the treatment of advanced malignancies, with great clinical application prospects.