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目的探讨兰索拉唑联合抗生素治疗酒精性消化溃疡的临床疗效。方法 76例酒精性消化溃疡患者,将其按照治疗措施的不同分为观察组38例和对照组38例,观察组采取兰索拉唑联合抗生素治疗,对照组患者采用奥美拉唑联合抗生素治疗。比较两组的临床疗效。结果观察组治疗总有效率为97.37%,不良反应发生率为7.89%;对照组治疗总有效率为73.68%,不良反应发生率为31.58%。两组比较差异均有统计学意义(P<0.05)。结论兰索拉唑联合抗生素治疗酒精性消化溃疡的临床疗效显著,且患者的不良反应较少,治疗安全性较高,值得在临床上推广使用。
Objective To investigate the clinical efficacy of lansoprazole combined with antibiotics in the treatment of alcoholic peptic ulcer. Methods A total of 76 patients with alcoholic peptic ulcer were divided into observation group (38 cases) and control group (38 cases). Patients in the observation group were treated with lansoprazole combined with antibiotics. Patients in the control group were treated with omeprazole combined with antibiotics . The clinical efficacy of the two groups was compared. Results The total effective rate was 97.37% in the observation group and 7.89% in the adverse reaction group. The total effective rate in the control group was 73.68% and the adverse reaction rate was 31.58%. The differences between the two groups were statistically significant (P <0.05). Conclusions Lansoprazole combined with antibiotics in the treatment of alcoholic peptic ulcer clinical significant effect, and patients with fewer adverse reactions, the treatment of high safety, it is worth promoting in clinical use.