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近期,Jani等在新英格兰杂志发表文章认为:J点抬高>0.2mV是早复极患者发生心脏性猝死的预警指标。其对10864例中年早复极综合征患者进行了30±11年的随访。早复极综合征须满足下壁或侧壁J点抬高≥0.1mV或>0.2mV,主要终点为全因死亡包括因心律失常引起。全组有630例(5.8%)患者的J点抬高≥0.1mV,其中384例(3.5%)位于下壁,262例(2.4%)位于侧壁,16例(0.1%)在下壁和侧壁均有J点抬高。下壁导联J点抬高至少0.1mV被证实与心脏性死亡有关(HR1.28,95%CI,1.04~1.59;p=0.03)。当下壁导联J点抬高>0.2mV时能明显增加心源性死亡的危险(HR2.98,95%CI,1.85~4.92;p<0.001)。
Recently, Jani et al published an article in the New England Journal that: J point elevation> 0.2mV is an early warning indicator of sudden cardiac death in patients with AP. It conducted 10 ± 11 years of follow-up of 10,864 middle-aged patients with early-repolarization syndrome. Early repolarization syndrome must meet the lower wall or sidewall J-point elevation ≥ 0.1mV or> 0.2mV, the main end point of all-cause mortality including due to arrhythmia. J points in all patients were elevated ≥ 0.1 mV in 630 patients (5.8%), 384 (3.5%) in the inferior wall, 262 (2.4%) in the lateral wall and 16 (0.1%) in the inferior and lateral walls J points are wall elevation. Lower J lead elevation of at least 0.1 mV was associated with cardiac death (HR 1.28, 95% CI, 1.04-1.59; p = 0.03). The J-point elevation> 0.2 mV of the inferior leads significantly increased the risk of cardiac death (HR 2.98, 95% CI, 1.85-4.92; p <0.001).